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KMID : 0861020080230020203
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Korea Journal of Herbology
2008 Volume.23 No. 2 p.203 ~ p.212
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The Study on Anti-hypertensive and Anti-diabetic Effect of Mori Ramulus
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Ham In-Hye
Jung Eun-sik
Lee Byong-hee
Choi Ho-Young
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Abstract
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Objecitivies: This study was performed to prove the anti-hypertensive and anti-diabetic effect of Mori Ramulus MR).
Methods: The examination was done on the femoral artery occlusion of the rat, and check the blood pressure. In addition, we observed therapueutic effects on diabetes rats induced by streptozotocin.
Results: MR MeOH Ex. showed few effect on descending blood pressure in SD rat model. MR CHCl3 layer (MRC) showed significant effect on descending blood pressure. MR was effective on the streptozotocin-induced diabetes SD rats. Especially MRC reduced the amount of serum glucose, BUN, triglyceride and insulin level.
Conclusions: MRC could induce descending blood pressure in the rat model. Also, it is expected to be effective in diabetes treatment.
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KEYWORD
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Scrophularia buergeriana, hypotensive effect, DNA analysis
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